Biocomputing may still be many years from its commercial applications, but its essential “weirdness” makes it an attractive source for speculative propositions right now. By probing possible scenarios of its everyday life materializations, we can figure out whether and how it will affect our understanding of computation, its spatial distributions, and its impacts on how we may interface with the natural world’s capacity to crunch numbers. We believe that the future of computation after silicon is tightly linked to the gradual “computational onboarding” of organisms and products of organic chemistry, as well as the intensification of the becoming environmental of computation, using the words of Jennifer Gabrys.^[1] As a result, the ability to compute may become an ambient property of our surroundings: a speculative proposition that enables a novel vision of architectural and design practices at the crossroads between biochemistry, digital media, and the built environment.